Eoghan O’Duibhir

This paper introduces a microscopy-based method to measure tumour-specific viability in neuroblastoma co-cultures and patient samples, enabling more accurate drug response assessment.

This study identifies Gcr2 as a Cdk8 substrate, showing its phosphorylation is critical for activating glycolysis genes.

The paper shows that RSC remodeler and pioneer factors work independently to position the +1 nucleosome at yeast promoters, facilitating transcription initiation through DNA sequence-directed action.