Maria J. Aristizabal

This study uses molecular dynamics and cryo-ET to show histone tails drive chromatin compaction through specific interactions, revealing their role in both structural organization and nucleosome communication.

The paper assesses the oncogenic potential of histone missense mutations using whole-exome sequencing data from over 12,000 cancer patients, finding that these mutations affect DNA repair interactions and increase mutagenesis.

This study surveys Canadian early-career health researchers to assess pandemic impacts, revealing high burnout rates and mental health declines.

This study identifies triglyceride as a key neutral lipid regulating spermatogenesis in Drosophila by showing that loss of the triglyceride lipase brummer leads to sperm developmental defects.

This study identifies Gcr2 as a Cdk8 substrate, showing its phosphorylation is critical for activating glycolysis genes.