Author

Farhad Shakeri

University of BonnORCID 0000-0003-1161-1942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Andreas BuneßiD· 2 shared Felix MeissneriD· 2 shared Adriana Geraci· 1 shared Alesja Dernst· 1 shared Alexander KruseiD· 1 shared Anne‐Kathrin GellneriD· 1 shared Ansgar PoetschiD· 1 shared Anshupa SahuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

Andreas BuneßORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 5, 2025

Cytohesin-2 is essential for the survival of mice and regulates Golgi volume and function

Carsten Küsters, Bettina Jux, Farhad Shakeri…·Waldemar Kolanus

This study shows that cytohesin-2 is essential for mouse survival and regulates Golgi volume and function through in vivo and in vitro analyses.

DOI 10.1101/2025.05.05.651226

mouseproteomics

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ImmunologyCell Death and DifferentiationPeer-reviewedSep 17, 2024

Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3-/- mice

Felix D. Weiss, Yubell Alvarez, Farhad Shakeri…·Felix Meissner

The paper identifies retention of 129S genome in Nlrp3-/- mice causing NLRP1 hypersensitivity and transcriptional changes, and introduces a conditional Nlrp3 allele to resolve phenotypes.

4 citations

mousebulk RNA-seq

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Molecular BiologyCellsPeer-reviewedJul 27, 2020

Prm2 deficiency triggers a Reactive Oxygen Species (ROS)-mediated destruction cascade during epididymal sperm maturation in mice

Simon Schneider, Farhad Shakeri, Christian Trötschel…·Hubert Schorle

This study investigates Prm2 deficiency in mice, showing it leads to oxidative stress and DNA damage during sperm maturation, affecting fertility.

44 citationstop 4%

mouseproteomics

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