Author

Massimo Breccia

Sapienza University of RomeORCID 0000-0003-1163-6162Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Angelisa FrascaiD· 1 shared Cecilia CabasinoiD· 1 shared Clara De PalmaiD· 1 shared Concetta De QuattroiD· 1 shared Cristina BattagliaiD· 1 shared Davide PozziiD· 1 shared Dimitrios MougiakakosiD· 1 shared E. Albizzati· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Angelisa FrascaORCID

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintJan 8, 2025

Phosphoproteomics reveals novel BCR::ABL1-independent mechanisms of resistance in chronic myeloid leukemia

Valeria Bica, Veronica Venafra, Giorgia Massacci…·Francesca Sacco

The paper identifies BCR::ABL1-independent survival mechanisms in CML using phosphoproteomics and computational analysis, highlighting FLT3 as a therapeutic target for TKI-resistant cases.

1 citation

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintFeb 8, 2023

Mecp2 knock-out astrocytes affect synaptogenesis by IL-6 dependent mechanisms

E. Albizzati, Elena Maria Florio, Massimo Breccia…·Angelisa Frasca

This study shows that Mecp2 knock-out astrocytes reduce synaptic density by secreting IL-6, which can be mitigated by blocking IL-6 activity.

1 citation

mouseexperimental assay

𝕏 PostBluesky