Davide Pozzi

This study shows that different subcellular distributions of UBE3A isoforms affect synaptic development and contribute to Angelman syndrome pathophysiology.

The paper identifies hypo- and hyperconnectivity subtypes in autism using cross-species fMRI, linking them to distinct biological mechanisms in mice and humans.

This study establishes a novel mouse model of prenatal IL-17A imprinting, showing embryo-restricted responses lead to behavioral deficits in offspring.

This study shows that Mecp2 knock-out astrocytes reduce synaptic density by secreting IL-6, which can be mitigated by blocking IL-6 activity.

This study investigates how 7q11.23 CNVs affect protein synthesis and neuronal excitability in neurodevelopmental disorders using patient-derived neurons and multi-omics approaches.

This study shows that enhancing neuronal activity rescues developmental defects in Mecp2 null neurons, improving their maturation and extending lifespan in a mouse model of Rett syndrome.

The paper shows that transient maternal IL-6 elevation during early neurodevelopment disrupts hippocampal connectivity and enhances glutamatergic synapses in offspring through the STAT3/RGS4 pathway.

The paper maps brain connectivity in 16 autism mouse models to identify four subtypes of functional connectivity abnormalities linked to different etiologies.