Caroline J. Zeiss

This study shows that double knockout of Vps13a and Vps13c in mice causes embryonic lethality due to impaired hematopoiesis and innate immune activation.

The paper develops OST inhibitors that selectively target STT3A and STT3B, leading to tumor regression in EGFR-mutant lung cancer models.

This study computes sex-specific survival curves for 12 nonhuman primate species to characterize aging patterns and provides insights into lifespan and healthspan differences.

The paper examines amygdalar tau binding and connectivity in preclinical Alzheimer's disease, finding associations with anxiety symptoms.

The paper identifies a loss-of-function mutation in the ABCA4 gene in Labrador retrievers with retinal degeneration, suggesting dogs as a model for human Stargardt disease.