Author

Haoxin Li

Scripps Research InstituteORCID 0000-0003-1247-5807Unclaimed ORCID profile · follow to get notified of new preprints

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Haoxin Li1 paper · Scripps Research Institute

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Stuart L. SchreiberiD· 2 shared Amy A. Deik· 1 shared Benjamin F. CravattiD· 1 shared Bingwen LuiD· 1 shared Bridget K. WagneriD· 1 shared Bruno N. MelilloiD· 1 shared Clary B. Clish· 1 shared Daisuke OgasawaraiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Stuart L. SchreiberORCID

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2 papers

Recent·Most cited

Systems BiologyNature Chemical BiologyPeer-reviewedOct 2, 2023

Assigning functionality to cysteines by base editing of cancer dependency genes

Haoxin Li, Tiantai Ma, Jarrett R. Remsberg…·Benjamin F. Cravatt

The paper uses base editing to assess the functional impact of cysteine mutations in cancer dependency genes, identifying essential and ligandable cysteines for drug development.

62 citationstop 2%

humanproteomics

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Cancer BiologybioRxivPreprintAug 9, 2018

HIF-2α drives an intrinsic vulnerability to ferroptosis in clear cell renal cell carcinoma

Yilong Zou, Michael J. Palte, Amy A. Deik…·Stuart L. Schreiber

This paper identifies a vulnerability in clear-cell renal cell carcinoma cells to ferroptosis induced by GPX4 inhibition, driven by the HIF-2-HILPDA pathway and PUFA-lipid enrichment.

DOI 10.1101/388041

humanproteomics

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