Harrison B. Cullen

This study shows that PNMA1 and PNMA4, derived from retrotransposons, are essential for reproductive capacity, as their absence leads to subfertility and hormonal changes in mice and associations with reproductive traits in humans.

The paper identifies a human protein of retroviral origin that restricts retroviral infection, showing its expression in embryos and placenta and its antiviral activity against type D retroviruses.

The paper reports the structure of virus-like capsids formed by Drosophila Arc proteins and shows their similarity to retroviral and retrotransposon capsids.