Ana Rita R. Maia

This study evaluates the efficacy of the MPS1 inhibitor NTRC 0066-0 against glioblastoma in vitro and in vivo, finding strong in vitro activity but no antitumor effect in mouse models.

This paper introduces OncoMimics, a peptide-based immunotherapy using molecular mimicry between commensal bacterial and tumor antigens to induce cross-reactive T cell responses, showing early clinical success in glioblastoma.

The paper identifies previously overlooked activating promoter mutations in cancer using a computational workflow applied to the PCAWG dataset, validating several candidates through luciferase assays.

This study profiles endometrial tissue from MRKH syndrome patients using RNA-seq to identify altered transcription patterns and candidate genes involved in the syndrome.