Author

Sandhya Srinivasan

Duke University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Adam W. J. SohiD· 1 shared Alireza Fotuhi SiahpiraniiD· 1 shared Amr A. AbdeeniD· 1 shared Benjamin SteyeriD· 1 shared Bikash Ranjan PattnaikiD· 1 shared Budd A. TuckeriD· 1 shared Cole Bacig· 1 shared David M. GammiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Adam W. J. SohORCID

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2 papers

Recent·Most cited

A complete collagen IV fluorophore knock-in toolkit reveals -chain diversity in basement membrane

Sandhya Srinivasan, Willam Ramos-Lewis, Mychel Morais, Qiuyi Chi, Adam W. J. Soh, E. G. Williams, Rachel Lennon, David R. Sherwood

The paper constructs a collagen IV fluorophore knock-in toolkit in C. elegans to study -chain diversity and basement membrane defects in collagen IV mutants.

bioRxiv · Dec 14, 2024 · PreprintDevelopmental Biology

Human iPSC modeling reveals mutation-specific responses to gene therapy in Best disease

Divya Sinha, Benjamin Steyer, Pawan Kumar Shahi, Katherine P. Mueller, Rasa Valiauga, Kimberly L. Edwards, Cole Bacig, Stephanie S. Steltzer, Sandhya Srinivasan, Amr A. Abdeen, Evan Cory, Viswesh Periyasamy, Alireza Fotuhi Siahpirani, Edwin M. Stone, Budd A. Tucker, , David M. Gamm

This study uses iPSC-RPE models to evaluate gene augmentation and editing for Best disease, finding that some mutations respond to gene therapy while others require genome editing.

bioRxiv · Jan 31, 2020 · PreprintGenetics