Author

Yu Zheng Chen

Sun Yat-sen UniversityORCID 0000-0003-1300-4652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Li ZhouiD· 2 shared Haofeng LiniD· 1 shared Huimin YaniD· 1 shared Jikai DengiD· 1 shared Jingyi YangiD· 1 shared Ke LaniD· 1 shared Lin LiuiD· 1 shared Meiqin LiuiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Li ZhouORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 26, 2025

A Novel 'Three-in-one' Mucosal Vaccine Elicits Broad Protection against Three Distinct Clusters of ACE2-using Sarbecoviruseses

Lin Liu, Haofeng Lin, Min Li…·Qingguo Wu

This paper develops a three-in-one mucosal vaccine, 3Rs-NC, that elicits broad neutralizing antibodies against three ACE2-using sarbecovirus clusters and provides durable protection in mice.

DOI 10.1101/2025.06.26.661659

mouseexperimental assay

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MicrobiologybioRxivPreprintNov 10, 2024

Generation of a biosafety mouse model infection for SARS-CoV-2 replicon delivery particles

Yingjian Li, Xiaoya Huang, Jikai Deng…·Yu Zheng Chen

The paper constructs a mouse model expressing SARS-CoV-2 N protein to study infection with SARS-CoV-2 replicon delivery particles, showing peak viral load and lung injury at 4 days post-infection.

2 citations

mousegenetic perturbation / CRISPR

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