Stéphanie Heux

This paper demonstrates that heterologous Pdu BMCs in E. coli can metabolize a broader range of diols and triols than previously known, including glycerol and up to 1,2-pentanediol, and shows their potential for biotechnological applications.

This study shows acetate can boost bioproduction in glucose-grown E. coli by reducing carbon loss, increasing acetyl-CoA levels, and improving biomass accumulation, validated for mevalonate and 3-hydroxypropionate.

The paper describes the engineering of Bacillus methanolicus to enhance L-glutamate and GABA production through systems-level analysis and metabolic engineering.

The paper develops a method to measure enzymatic parameters in vivo using synthetic biology tools and applies it to study carotenoid pathway enzymes in yeast.

PhysioFit quantifies cell growth parameters and extracellular fluxes using flexible growth models and provides a user-friendly software tool for non-computational biologists.

This study characterizes the ethanolamine utilization BMC in E. coli using genetic, omics, and modeling approaches, revealing ethanolamine as a dual carbon and nitrogen source.

The paper performs 13C metabolic flux analysis on B. methanolicus to compare methylotrophic and non-methylotrophic metabolic states and better understand its metabolism.

The paper designs a synthetic methanol utilization pathway in E. coli by combining methylotrophic enzymes from different sources and optimizing it for increased methanol assimilation.

ScalaFlux quantifies metabolic fluxes in subnetworks without requiring external network information, validated on yeast mutants and simulated data.