Vanessa Soldan

Small but Mighty: The Surprising Metabolic Range of a Bacterial Microcompartment

This paper demonstrates that heterologous Pdu BMCs in E. coli can metabolize a broader range of diols and triols than previously known, including glycerol and up to 1,2-pentanediol, and shows their potential for biotechnological applications.

Organelle distribution and protein translation defects in radial glia cells with mutations in Eml1

The paper investigates Eml1 mutations in mice, finding altered organelle distribution and translation defects in radial glia cells, contributing to subcortical heterotopia.

Pera virus mimics bacteria to infect Pedopumella sp. a freshwater heterotrophic Chrysophyceae

The paper describes Pera virus, a giant virus infecting Pedospumella sp., and reports its morphological features and ecological dynamics in freshwater lakes.

The phosphoinositide PI5P impairs mitochondrial function through endosome-mitochondria proximity

This study shows that PI5P causes mitochondrial fragmentation and dysfunction in cardiomyocytes under metabolic stress, linking endolysosomal signaling to mitochondrial metabolism.

VEXAS anemia is a mosaic erythroblastopenia

This study investigates VEXAS anemia, showing that UBA1 mutations affect erythroblast differentiation but not mature red cells, leading to a mosaic erythroblastopenia.

Promiscuous structural cross-compatibilities between major shell components of Klebsiella pneumoniae bacterial microcompartments

This study identifies structural cross-compatibilities between BMC-H paralogs in Klebsiella pneumoniae, revealing hetero-hexamer formation and reinterpreting existing mass spectrometry data.

Integrative in vivo analysis of the ethanolamine utilization bacterial microcompartment in Escherichia coli.

This study characterizes the ethanolamine utilization BMC in E. coli using genetic, omics, and modeling approaches, revealing ethanolamine as a dual carbon and nitrogen source.