Author

Ali Roghanian

BioInvent (Sweden)ORCID 0000-0003-1316-4218Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:structural biology· 1

Frequent Co-Authors

Alex LookiD· 1 shared Andrew Chancellor· 1 shared Andrew WhiteiD· 1 shared Björn FrendéusiD· 1 shared Bruno LinclauiD· 1 shared Daniel J. Burns· 1 shared Hatice Nurdan Aksoy KilinciD· 1 shared Ivo TewsiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alex LookORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 25, 2025

Ligand-responsive groove remodelling in human and macaque CD1d reveals a conserved MHC-like gating mechanism

Daniel J. Burns, Alex Look, Steven Turner…·Salah Mansour

This study determines the crystal structures of human and macaque CD1d bound to -GalCer, revealing conserved ligand-responsive conformational flexibility at Phe84 that modulates antigen presentation.

DOI 10.64898/2025.12.23.695970

humannon-human primate

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NeurosciencebioRxivPreprintNov 18, 2025

Deletion or Targeted Blockade of FcγRIIb (CD32b) Impairs α-Syn Propagation In-Vivo

James M. Hennegan, Michael J. Hurley, Kerry L. Cox…·Jessica L. Teeling

This study shows that FcγRIIb promotes α-syn propagation and neurotoxicity in vivo, suggesting it as a therapeutic target for synucleinopathies.

DOI 10.1101/2025.11.18.687143

mouseexperimental assay

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