Author

Steven Turner

University of SouthamptonORCID 0000-0002-2913-7532Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Jonathan W. EssexiD· 3 shared Oliver J. MellingiD· 2 shared Alex LookiD· 1 shared Ali RoghanianiD· 1 shared Andrew Chancellor· 1 shared Andrew G. JamiesoniD· 1 shared Andrew WhiteiD· 1 shared Andy van HatereniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

Jonathan W. EssexORCID

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Author profile →

3 papers

Recent·Most cited

Structures of muscle-type nicotinic acetylcholine receptor with α-conotoxins reveal determinants of receptor-subtype specificity

Michael J. Capper, Oscar A. Shepperson, Charlie Holdship, Oliver J. Melling, Nicola Wade, Michael A. Malone, Kirsty Arnott, Leonie M. Windeln, Steven Turner, Charlotte L. Whitmore, Tiffany Morcom, Josephine Connah, Christopher M. Timperley, Jeremy Graham Frey, C. Green, , Andrew G. Jamieson

The paper determines the molecular basis of -conotoxin specificity for muscle-type nAChRs using cryo-EM structures and computational methods.

bioRxiv · Jan 15, 2026 · PreprintMolecular Biology

Ligand-responsive groove remodelling in human and macaque CD1d reveals a conserved MHC-like gating mechanism

Daniel J. Burns, Alex Look, Steven Turner, Martin Maly, Oliver J. Melling, Kinga Niedobecka, Rita Szoke‐Kovacs, Hatice Nurdan Aksoy Kilinc, Richard J. Suckling, Andrew Chancellor, Mariolina Salio, Andrew White, Sally A. Sharpe, Ali Roghanian, Bruno Linclau, , Salah Mansour

This study determines the crystal structures of human and macaque CD1d bound to -GalCer, revealing conserved ligand-responsive conformational flexibility at Phe84 that modulates antigen presentation.

bioRxiv · Dec 25, 2025 · PreprintImmunology

Atom-level mechanism of tapasin-independent peptide editing by Major Histocompatibility Complex class I molecules

Steven Turner, Rachel Darley, Jonathan W. Essex, Malcolm J. W. Sim, Andy van Hateren, Tim J Elliott

The paper investigates tapasin-independent peptide editing by MHC-I molecules using molecular dynamics simulations, revealing an 'active displacement' mechanism that explains peptide selection and immunogenic epitope presentation.

bioRxiv · Jun 20, 2025 · PreprintImmunology