Author

Daniel J. Burns

University of Southampton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:non-human primate· 1 Assay:structural biology· 1

Frequent Co-Authors

Alex LookiD· 1 shared Ali RoghanianiD· 1 shared Andrew Chancellor· 1 shared Andrew WhiteiD· 1 shared Bruno LinclauiD· 1 shared Hatice Nurdan Aksoy KilinciD· 1 shared Ivo TewsiD· 1 shared Jonathan W. EssexiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alex LookORCID

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1 paper

Recent·Most cited

Ligand-responsive groove remodelling in human and macaque CD1d reveals a conserved MHC-like gating mechanism

Daniel J. Burns, Alex Look, Steven Turner, Martin Maly, Oliver J. Melling, Kinga Niedobecka, Rita Szoke‐Kovacs, Hatice Nurdan Aksoy Kilinc, Richard J. Suckling, Andrew Chancellor, Mariolina Salio, Andrew White, Sally A. Sharpe, Ali Roghanian, Bruno Linclau, , Salah Mansour

This study determines the crystal structures of human and macaque CD1d bound to -GalCer, revealing conserved ligand-responsive conformational flexibility at Phe84 that modulates antigen presentation.

bioRxiv · Dec 25, 2025 · PreprintImmunology