Author

Sivarajan Kumarasamy

Ohio UniversityORCID 0000-0003-1327-2294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Agnes O PortuphyiD· 2 shared Getachew Debas BelewiD· 2 shared Raziyeh Abdolahipour· 2 shared Sobia ZaidiiD· 2 shared Sonia Michael NajjariD· 2 shared Abhishek P ShresthaiD· 1 shared Ali ZarrinpariD· 1 shared Amira F. GoharaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

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10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintNov 23, 2025

Defective insulin clearance plays a primary role in the pathogenesis of chronic kidney disease in mice with null deletion of Ceacam2 gene

Sivarajan Kumarasamy, Getachew Debas Belew, Agnes O Portuphy…·Sonia Michael Najjar

This study shows that loss of CEACAM2 in mice impairs renal insulin clearance, leading to hyperinsulinemia, insulin resistance, and kidney dysfunction.

1 citation

mouseexperimental assay

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PhysiologyMolecular MetabolismPeer-reviewedAug 19, 2024

Conditional deletion of CEACAM1 causes hepatic stellate cell activation

Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla…·Sonia Michael Najjar

This study shows that CEACAM1 loss in hepatic stellate cells (HSCs) activates them, leading to myofibroblastic transformation and fibrosis without insulin resistance or steatosis.

18 citations

mouseexperimental assay

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