Author

Rosalyn W. Sayaman

City Of Hope National Medical CenterORCID 0000-0003-1343-0619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Elad ZiviD· 2 shared Alessandro ScapozzaiD· 1 shared Alfonso ValenciaiD· 1 shared Allen MaoiD· 1 shared Amy LeungiD· 1 shared Camila D. Arcuschin· 1 shared Candi Trac· 1 shared Carolina Di BenedettoiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Elad ZivORCID

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4 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 27, 2026

Characterization of the somatic landscape and transcriptional profile of breast tumors from 748 Hispanic/Latina women in California

Yuanchun Ding, Rosalyn W. Sayaman, Denise M. Wolf…·Elad Ziv

The paper analyzes somatic mutations and transcriptional profiles in breast tumors from 748 Hispanic/Latina women, finding differences in tumor immune microenvironment ecotypes linked to ancestry and APOBEC3A/B copy-number deletions.

DOI 10.64898/2026.02.13.26346286

humanwhole-exome sequencing

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Cancer BiologyCellular and Molecular Life SciencesPeer-reviewedNov 13, 2025

Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype

Camila D. Arcuschin, Kamin Kahrizi, Rosalyn W. Sayaman…·Denise P. Muñoz

The paper identifies ThPOK/ZBTB7B as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype by suppressing metastatic pathways.

2 citations

humanbulk RNA-seq

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GenomicsbioRxivPreprintSep 28, 2020

The landscape of interactions between cancer polygenic risk scores and somatic alterations in cancer cells

Eduard Porta‐Pardo, Rosalyn W. Sayaman, Elad Ziv, Alfonso Valencia

This study examines how cancer polygenic risk scores correlate with somatic alterations in tumors from The Cancer Genome Atlas, revealing associations with specific molecular subtypes and driver events.

7 citations

humanwhole-genome sequencing

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GenomicsbioRxivPreprintJun 26, 2020

Normal mammary epithelia accumulate DNA methylation changes with age that are consistent with breast cancer methylomes

Parijat Senapati, Masaru Miyano, Rosalyn W. Sayaman…·Dustin E. Schones

This study identifies age-related DNA methylation changes in luminal mammary epithelial cells that correlate with breast cancer methylomes and contribute to lineage fidelity loss.

4 citations

humanDNA methylation

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