Xue Xiao

The paper shows that REST elevation in cerebellar granule cell progenitors increases chromatin accessibility, alters Grk6 transcript expression, and hyperactivates Cxcr4-Sdf1 signaling, leading to increased cell migration.

The paper uses CRISPRi-seq to identify FprB as a synergistic target for gallium therapy in Pseudomonas aeruginosa, enhancing gallium's efficacy against infections.

This paper reviews and benchmarks NGS-based computational methods for predicting transcriptional regulators using query gene sets, finding that BART, ChIP-Atlas, and Lisa perform best.

The paper identifies a stress-specific erythroid progenitor population that links regenerative erythropoiesis to pathogenic erythrocytosis through Epo-IGF1R crosstalk.