Lisa A. Cavacini

This paper identifies a conserved epitope on OspA that is broadly protective against multiple Borrelia genospecies, suggesting a basis for a universal Lyme disease vaccine.

This study identifies protective antibodies against Mycobacterium tuberculosis and shows that their Fc-effector function and Fab domains collaborate to restrict infection through immune cell reorganization.

This study identifies a type-specific B cell epitope on OspC type A of Borreliella burgdorferi and shows its role in antibody-mediated motility inhibition.

This study determines the structure of a human monoclonal antibody in complex with OspC from Borreliella burgdorferi, revealing its epitope and interaction mechanism.

The paper identifies unique borreliacidal epitopes on OspA using VHHs and evaluates their reactivity across OspA serotypes.

This study generates transgenic goats producing an improved cetuximab in milk, showing enhanced therapeutic properties and safety compared to existing treatments.