Author

Carter J. Hoffman

University of California, Los AngelesORCID 0000-0003-1441-4143Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Angeliki Diotima IoannidisiD· 1 shared Anoushka Kathiravan· 1 shared Evelyn ArambulaiD· 1 shared Frank PajonkiD· 1 shared Harley I. KornblumiD· 1 shared Julian P. WhiteleggeiD· 1 shared Linda M. LiauiD· 1 shared Ling HeiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Angeliki Diotima IoannidisORCID

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1 paper

Recent·Most cited

NeuroscienceCancer Research CommunicationsPeer-reviewedJun 5, 2024

Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1

Ling He, Angeliki Diotima Ioannidis, Evelyn Arambula…·Frank Pajonk

This study shows that activation of the mevalonate pathway and Rac-1 in glioblastoma cells after anti-cancer treatments promotes recurrence, and statins combined with radiation improve survival in mouse models.

5 citations

mousebulk RNA-seq

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