Author
The University of Texas MD Anderson Cancer CenterORCID 0000-0003-1442-1589Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Nazanin Esmaeili Anvar, Chenchu Lin, Xingdi Ma…·Traver Hart
The paper introduces the in4mer CRISPR/Cas12a platform for efficient multiplex gene knockout, demonstrating improved sensitivity and reduced clone numbers compared to CRISPR/Cas9.
Lance C. Novak, Juihsuan Chou, Medina Colic…·Traver Hart
PICKLES v3 provides an updated database of CRISPR knockout screens in human cell lines, enabling exploration of gene fitness across multiple libraries and cell lines.
W. Frank Lenoir, Micaela Morgado, Peter C DeWeirdt…·Traver Hart
The paper identifies novel tumor suppressors from CRISPR screens and reveals rewired lipid metabolism in AML cells through functional analysis of gene modules.
Eiru Kim, Merve Dede, W. Frank Lenoir…·Traver Hart
The paper constructs a coessentiality network from CRISPR knockout screens to infer gene function and reveal hierarchical cell organization.
Medina Colic, Gang Wang, Michal Zimmermann…·Traver Hart
drugZ identifies chemogenetic interactions from CRISPR screens, finding more homologous recombination repair pathway genes and confirming KEAP1 loss as a resistance factor for ERK inhibitors.