Author

Jingyi Shi

Ministry of Education of the People's Republic of ChinaORCID 0000-0002-9972-7263Unclaimed ORCID profile · follow to get notified of new preprints

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Jingyi Shi1 paper · Peking University

Biology Disciplines

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Biophysics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:E. coli· 1 Assay:electrophysiology· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexander I. SobolevskyiD· 1 shared Hao WangiD· 1 shared Hong CheniD· 1 shared Irina A. TalyzinaiD· 1 shared Jianmin CuiiD· 1 shared Jie ZhengiD· 1 shared Kevin Xu· 1 shared Lei CheniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

Alexander I. SobolevskyORCID

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2 papers

Recent·Most cited

Genome-wide A to G and C to T Mutations Induced by Functional TadA Variants in Escherichia coli

Hao Wang, Zhengxin Dong, Jingyi Shi, Lei Chen, Tao Sun, Weiwen Zhang

This paper develops a system for inducing A[->]G and C[->]T mutations in E. coli using fusion proteins of DnaG with TadA variants, significantly increasing mutation rates and enabling rapid adaptive evolution.

ACS Synthetic Biology · Jan 9, 2025Peer-reviewedSynthetic Biology

Human TRPV4 engineering yields an ultrasound-sensitive actuator for sonogenetics

Lu Zhao, Kevin Xu, Irina A. Talyzina, Jingyi Shi, Shisheng Li, Yaoheng Yang, Shuming Zhang, Jie Zheng, Alexander I. Sobolevsky, Hong Chen, Jianmin Cui

The paper engineers hTRPV4 to create an ultrasound-sensitive actuator for sonogenetics, showing improved mechano-sensitivity and reduced sensitivity to other stimuli.

bioRxiv · Oct 16, 2024 · PreprintBiophysics