Raymond Kiu

This study uses long-read metagenomics to analyze the microbiome and resistome in advanced chronic liver disease, identifying Enterococcus faecium dominance and resistance gene enrichment linked to disease severity.

The paper identifies a CD87-dependent coagulation pathway that enhances Th17 potential in neonatal cDC2, with implications for early-life immunity.

This study shows maternal gut microbiota influences neonatal retinal angiogenesis via lactational metabolic signals, with choline and lipid metabolites playing a key role.

The paper identifies a novel gene cluster in Bifidobacterium pseudolongum that enables resistant starch utilization, linking CAZyme profiles to niche adaptation in infant and adult microbiomes.

This study analyzes prophages and defense systems in Bifidobacterium genomes to reveal co-evolutionary 'arms race' dynamics between bacteria and phages.

This study identifies host-specific genomic and microbiome adaptations in Bifidobacterium across diverse animal hosts, revealing co-evolutionary dynamics and functional traits shaped by diet and phylogeny.

This study examines how early antibiotic and probiotic treatments affect the gut microbiome and resistome in preterm infants, finding that probiotics reduce antibiotic resistance genes and MDR pathogens but do not eliminate them.

This study identifies Staphylococcus haemolyticus as a common gut colonizer in preterm infants and reveals its role as a reservoir of antibiotic resistance genes through genomic analysis.

The paper shows that Escherichia coli and Bifidobacterium bifidum have a mutualistic interaction in degrading human milk oligosaccharides in healthy infants.

The paper identifies Clostridium species that metabolize human milk oligosaccharides, producing beneficial metabolites and suppressing inflammation and pathogen growth in preterm infants.

This study shows that infant gut microbiota at 1 month are most responsive to dietary changes, while 18-month-olds show resilience, with formula affecting fewer metabolic pathways than breast milk.

This study shows that maternal colonization with Bifidobacterium breve during pregnancy alters fetal brain metabolism and expression of key pathways.

The paper describes an optimized DNA extraction method for skin swabs suitable for shotgun metagenomics, validated on adult and baby samples to characterize bacterial microbiota effectively.