Author

Yongxian Wu

University of California, IrvineORCID 0000-0003-1497-2444Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:protein design· 1

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Derek AspacioiD· 1 shared Edward J. King· 1 shared Emma LuuiD· 1 shared Han LiiD· 1 shared Justin B. SiegeliD· 1 shared Qiang ZhuiD· 1 shared Ray LuoiD· 1 shared Sean PereaiD· 1 shared

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1 shared paperSynthetic Biology

Derek AspacioORCID

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1 paper

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Synthetic BiologyNature Chemical BiologyPeer-reviewedAug 13, 2024

Shifting Redox Reaction Equilibria on Demand Using an Orthogonal Redox Cofactor

Derek Aspacio, Yulai Zhang, Youtian Cui…·Han Li

This paper introduces Nox Ortho, an enzyme that enables precise control of redox reactions using NMN+ as a cofactor, achieving high specificity and enabling chiral-pure product synthesis.

44 citationstop 2%

E. coliexperimental assay

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