Qiang Chen

This study compares the antiviral activities of neutralizing and non-neutralizing mAbs against SARS-CoV-2, showing that Fc glycosylation significantly impacts antiviral efficacy through ADCC and ADCVI.

This study shows that directional myelin growth in zebrafish is driven by a Wnt4b gradient and is essential for proper axon function and behavior.

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

This study expresses glycoengineered pentameric SARS-CoV-2 IgMs in plants, showing 390-fold increased neutralization potency compared to IgG1 orthologues.