Kuan‐Ting Lin

This study shows CDK11 is critical for cancer cell survival and identifies 1p36 deletions as a biomarker for CDK11 inhibitor sensitivity, but on-target toxicity limits therapeutic efficacy.

The paper systematically characterizes short intronic splicing-regulatory elements by analyzing their effects on exon splicing using a minigene approach.

The paper identifies a human-specific switch in AFMID isoforms linked to TP53 mutations and HCC recurrence through splicing changes analyzed in RNA-Seq datasets.

The paper identifies de novo intronic indels in autism target genes from simplex families and finds they contribute to at least 10% of simplex autism.