Author

Matthew J. Langton

University of OxfordORCID 0000-0003-1555-3479Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

Aidan KerckhoffsiD· 1 shared Eric SefahiD· 1 shared Hagan BayleyiD· 1 shared Jacob K. HiltoniD· 1 shared Joanne L. ParkeriD· 1 shared Jorin RiexingeriD· 1 shared Joseph A. MindelliD· 1 shared Justin C. DemeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiophysics

Aidan KerckhoffsORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 1, 2025

Mechanism of phosphoinositide regulation of lysosomal pH via inhibition of CLC-7

Jacob K. Hilton, Yifei Lin, Eric Sefah…·Joseph A. Mindell

The paper investigates how PI(3,5)P2 regulates lysosomal pH by inhibiting ClC-7, showing structural changes in ClC-7 upon PI(3,5)P2 binding and linking this to disease mutations.

1 citation

humanproteomics

𝕏 PostBluesky

BiophysicsNature NanotechnologyPeer-reviewedJan 21, 2025

ON-OFF nanopores for optical control of transmembrane ionic communication

Xiankai Wang, Aidan Kerckhoffs, Jorin Riexinger…·Yujia Qing

This paper describes the creation of photopores that switch between iontronic resistor and diode modes using light, enabling optical control of transmembrane ionic communication.

19 citationstop 5%

experimental assaysynaptic & neural circuits

𝕏 PostBluesky