Author

Michael J. Lenardo

National Institutes of HealthORCID 0000-0003-1584-468XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alan Thomas RemaleyiD· 1 shared Alyssa GroganiD· 1 shared Ann Y. ParkiD· 1 shared Bernd J. WranikiD· 1 shared Bryan King· 1 shared Bryson D. BennettiD· 1 shared Christa S. ZerbeiD· 1 shared Christopher W. WhelaniD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alan Thomas RemaleyORCID

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2 papers

Recent·Most cited

ImmunologyCellPeer-reviewedOct 1, 2026

Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

Xiang Chen, Kaja S. Arusha, Danielle Springer…·Michael J. Lenardo

This study shows that GIMAP6 loss leads to inflammatory vasculopathy and atherosclerosis, causing heart failure and early death, and identifies GIMAP6 as a protective factor against cardiovascular disease.

DOI 10.1016/j.cell.2026.09.032

humanexperimental assay

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GenomicsbioRxivPreprintAug 3, 2020

Insights into dispersed duplications and complex structural mutations from whole genome sequencing 706 families

Christopher W. Whelan, Robert E. Handsaker, Giulio Genovese…·Steven A. McCarroll

The paper identifies dispersed duplications and de novo structural mutations using whole-genome sequencing data from 706 families by analyzing IBD relationships and copy number variations.

1 citation

humanwhole-genome sequencing

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