Henrietta Holze

The paper integrates single-cell proteomics and transcriptomics to study human hematopoietic stem and progenitor cells, identifying protein markers and dynamics not captured by mRNA alone.

The paper shows that inhibiting KAT6/KAT7 enhances Menin inhibitor efficacy and overcomes resistance in MLL-FP leukemia.

This paper introduces an interpretable cell mapping strategy to align and compare heterogeneous spatial data across different scales and contexts, showing spatiotemporal decoupling during development and identifying subpopulations in cancer patient data.

BARtab and bartools provide a scalable pipeline and R package for analyzing synthetic cellular barcodes in genomic and transcriptomic data.

This study identifies genetic loci and candidate genes associated with cuticular hydrocarbon variation in parasitoid wasps, revealing genomic regions linked to methyl-branched alkane biosynthesis.