Courtney E McDougal

This study shows that lymphatic networks create spatially distinct environments in draining lymph nodes that influence B cell differentiation, affinity selection, and antibody isotype, which can be manipulated through vaccine design.

The paper shows that the repetitive structure of the Plasmodium CSP protein affects B cell memory, leading to reduced humoral immunity over time.

This study shows that nanoparticle vaccines with oligomannose glycans boost B cell responses and protection against malaria sporozoites compared to other glycan types.

The paper identifies BCL6 and CD4+ T cell dependence in generating functional IgM+ memory B cells independent of germinal center formation.