Author

Siddharth Narendran

Aravind Eye HospitalORCID 0000-0002-9220-8049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Felipe PereiraiD· 2 shared Jayakrishna AmbatiiD· 2 shared Albert S. JuniD· 1 shared Austin D. BohneriD· 1 shared Balamurali Krishna AmbatiiD· 1 shared Bonnie J. Archer· 1 shared Bradley D. GelfandiD· 1 shared Guangping GaoiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Felipe PereiraORCID

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2 papers

Recent·Most cited

The learning curve of murine subretinal injection among clinically trained ophthalmic surgeons

Peirong Huang, Siddharth Narendran, Felipe Pereira, Shin‐ichi Fukuda, Yosuke Nagasaka, Ivana Apicella, Praveen Yerramothu, Kenneth M. Marion, Xiaoyu Tracy Cai, Srinivas Reddy Sadda, Bradley D. Gelfand, Jayakrishna Ambati

This paper evaluates the learning curve for subretinal injection in mice among ophthalmic surgeons, finding a significant improvement in success rate after 364 training cases.

Translational Vision Science & Technology · Mar 11, 2022Peer-reviewedNeuroscience

Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

Hironori Uehara, Xiaohui Zhang, Felipe Pereira, Siddharth Narendran, Susie Choi, Sai Bhuvanagiri, Jinlu Liu, Sangeetha Ravi Kumar, Austin D. Bohner, Lara S. Carroll, Bonnie J. Archer, Yue Zhang, Wei Liu, Guangping Gao, Jayakrishna Ambati, , Balamurali Krishna Ambati

This study shows that CRISPR/Cas9 gene editing in adult mice prevents vision loss in a model of Fuchs' endothelial corneal dystrophy by disrupting the start codon of the mutant COL8A2 gene.

eLife · Jun 8, 2021Peer-reviewedGenomics