Jiajie Shao

The paper shows that loss of neuropeptide signaling in C. elegans leads to increased muscle excitability via CaV1 channels to compensate for reduced cholinergic transmission.

The paper investigates how RIM and RIM-binding proteins regulate synaptic transmission by localizing Cav2 channels in C. elegans neuromuscular junctions, showing differential effects on cholinergic and GABAergic transmission.

This study shows that synapsin SNN-1 is required for cAMP-dependent neuropeptide release in C. elegans motor neurons by capturing dense core vesicles at synapses.