Kynurenic acid promotes activity-dependent synaptic pruning in schizophrenia
Funda Orhan, Susmita Malwade, Neda Khanlarkhani…·Carl M. Sellgren
This study shows that kynurenic acid promotes microglia-mediated synaptic pruning in schizophrenia by reducing neuronal activity and linking genetic risk variants to KYNA production.