Author

Takahiro M. Ishii

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & TechnologyORCID 0000-0003-1664-6191Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew David DisneyiD· 2 shared Xueyi YangiD· 2 shared Amirhossein TaghaviiD· 1 shared Jielei WangiD· 1 shared Kisu SungiD· 1 shared Martina PedriniiD· 1 shared Patrick R. A. ZanoniD· 1 shared Ryuichi Sekioka· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Matthew David DisneyORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 26, 2026

Programmable Recruitment of RNA-Binding Proteins Enables Small Molecule-Directed Destabilization of Nuclear Pre-mRNA

Xiaoxuan Su, Jielei Wang, Takahiro M. Ishii…·Matthew David Disney

This paper develops a programmable platform to recruit RNA-binding proteins using small molecules, enabling RNA destabilization, and demonstrates its application to MAPT pre-mRNA.

DOI 10.64898/2026.08.25.746729

humanexperimental assay

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BiochemistrybioRxivPreprintNov 6, 2025

RNA-Focused DNA-Encoded Library Construction, Screening, and Integration of Docking Identify Bioactive Ligands of Pathogenic r(G4C2)exp RNA

Xueyi Yang, Amirhossein Taghavi, Yoshihiro Akahori…·Matthew David Disney

The paper identifies bioactive ligands for the toxic r(G4C2)exp RNA using DNA-encoded libraries combined with docking and SAR analysis.

DOI 10.1101/2025.11.06.686979

DNA methylationproteomics

𝕏 PostBluesky