Author

Ryuichi Sekioka

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

Matthew David DisneyiD· 2 shared Xiaoxuan SuiD· 2 shared Xueyi YangiD· 2 shared Amirhossein TaghaviiD· 1 shared Jessica L. Childs‐DisneyiD· 1 shared Jielei WangiD· 1 shared Kisu SungiD· 1 shared Patrick R. A. ZanoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

Matthew David DisneyORCID

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2 papers

Recent·Most cited

Programmable Recruitment of RNA-Binding Proteins Enables Small Molecule-Directed Destabilization of Nuclear Pre-mRNA

Xiaoxuan Su, Jielei Wang, Takahiro M. Ishii, Kisu Sung, Ryuichi Sekioka, Xueyi Yang, Patrick R. A. Zanon, Zhonglin Liu, Matthew David Disney

This paper develops a programmable platform to recruit RNA-binding proteins using small molecules, enabling RNA destabilization, and demonstrates its application to MAPT pre-mRNA.

bioRxiv · Aug 26, 2026 · PreprintBiochemistry

Live-Cell Covalent Profiling Reveals Principles of RNA-Small Molecule Recognition across the Human Transcriptome

Yuquan Tong, Amirhossein Taghavi, Xiaoxuan Su, Xueyi Yang, Warren B. Rouse, Sandra Kovachka, Jessica L. Childs‐Disney, Ryuichi Sekioka, Rey Zavala, Yanjun Li, Walter N. Moss, Matthew David Disney

The paper develops a live-cell method to identify RNA-small molecule interactions and uses it to design selective RNA degraders.

bioRxiv · Nov 5, 2025 · PreprintBiochemistry