Author

Takayuki Koyano

Shigei Medical Research InstituteORCID 0000-0003-1675-2525Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Makoto MatsuyamaiD· 3 shared Kei‐ichiro IshiguroiD· 2 shared Masahito IkawaiD· 2 shared Seiya OuraiD· 2 shared Ayako IsotaniiD· 1 shared Channabasavaiah B. GurumurthyiD· 1 shared Chisato KoderaiD· 1 shared Hiromi MiuraiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersDevelopmental Biology

Makoto MatsuyamaORCID

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3 papers

Recent·Most cited

Trim41 is essential for preventing X chromosome chaotic synapsis in male mice

Seiya Oura, Toshiaki Hino, Takashi Satoh, Taichi Noda, Takayuki Koyano, Ayako Isotani, Makoto Matsuyama, Shizuo Akira, Kei‐ichiro Ishiguro, Masahito Ikawa

This study shows that Trim41 prevents chaotic X chromosome synapsis in male mice, leading to infertility when disrupted.

bioRxiv · Nov 3, 2021 · PreprintDevelopmental Biology

KCTD19 associates with ZFP541 and HDAC1 and is required for meiotic exit in male mice

Seiya Oura, Takayuki Koyano, Chisato Kodera, Yuki Takada-Horisawa, Makoto Matsuyama, Kei‐ichiro Ishiguro, Masahito Ikawa

The paper identifies KCTD19 as essential for meiotic exit in male mice, showing it interacts with ZFP541 and HDAC1, and its deficiency causes apoptosis during meiosis.

PLoS Genetics · May 7, 2021Peer-reviewedDevelopmental Biology

In situ genome editing method suitable for routine generation of germline modified animal models

Masato Ohtsuka, Masahiro Sato, Hiromi Miura, Shuji Takabayashi, Makoto Matsuyama, Takayuki Koyano, Naomi Arifin, Shingo Nakamura, Kenta Wada, Channabasavaiah B. Gurumurthy

This paper improves the GONAD method for in situ genome editing, achieving efficiency comparable to microinjection for generating germline modified animal models.

Genome biology · Feb 26, 2018Peer-reviewedGenomics