DARPP-32 in motor cortex regulates structural and synaptic plasticity in corticothalamic neurons and enables motor learning.
Clarissa Anna Pisanò, Alina Aaltonen, Valeria Spanu…·Anders Borgkvist
This study shows that DARPP-32 in motor cortex is essential for synaptic plasticity and motor learning by regulating dendritic spines and long-term potentiation in corticothalamic neurons.