Ana Rita Brochado

This study shows that human-targeted drugs can both enhance antibiotic resistance and inhibit Campylobacter jejuni growth through efflux pump activation and direct toxicity.

The paper investigates how human-targeted drugs alter regulatory networks in Salmonella Typhimurium, revealing non-antibiotic compounds reshape virulence and antibiotic resistance through specific transcriptional responses.

The paper systematically characterizes transport regulation in E. coli across 94 chemical cues, revealing new transcriptional responses and the role of regulators like Rob.

This paper introduces a deep learning framework for antimicrobial discovery that identifies new compounds with antimicrobial potential using pre-trained molecular representations.

DGrowthR provides a statistical framework for analyzing large-scale microbial growth data, enabling differential growth analysis and discovery of compounds affecting bacterial growth.

The paper shows how species in gut bacterial communities can survive or go extinct based on resource availability and metabolic interactions, identifying emergent survival and community-driven extinctions.