Hung-Jhen Chen

This study defines zebrafish meningeal development, identifies conserved Foxc1 and Wnt signaling roles, and reveals limited regenerative capacity and developmental defects upon meningeal loss.

The paper shows how three signaling pathways coordinate to establish distinct cell fates along the oral-aboral axis in the developing zebrafish jaw.

This study identifies the role of BMP antagonists in sustaining mandibular growth in zebrafish by regulating chondrocyte differentiation and cartilage organization.

This study shows adult zebrafish can regenerate jaw joint ligaments without scarring through dedifferentiation of ligamentocytes and ECM remodeling, with legumain playing a key role.

The paper integrates single-cell transcriptome and chromatin accessibility data from zebrafish cranial neural crest cells across their lifetime to identify region-specific chromatin remodeling and lineage-priming factors.

This study maps the cellular diversity of the embryonic mouse coronal suture using single-cell transcriptomics, identifying key markers and cell types involved in suture development and fusion.