Kuo-Chang Tseng

Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration

This study shows adult zebrafish can regenerate jaw joint ligaments without scarring through dedifferentiation of ligamentocytes and ECM remodeling, with legumain playing a key role.

Lifelong single-cell profiling of cranial neural crest diversification

The paper integrates single-cell transcriptome and chromatin accessibility data from zebrafish cranial neural crest cells across their lifetime to identify region-specific chromatin remodeling and lineage-priming factors.

The developing mouse coronal suture at single-cell resolution

This study maps the cellular diversity of the embryonic mouse coronal suture using single-cell transcriptomics, identifying key markers and cell types involved in suture development and fusion.

Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation

The paper identifies Foxc1's role in establishing chromatin accessibility for facial cartilage enhancers during zebrafish development.