Christina Toft

This study evolves a plant RNA virus in age-diverse host populations and finds that host age structure drives virulence evolution by shaping disease progression, severity, and viral load.

This study investigates how chronic Orsay virus infection in C. elegans leads to age-dependent immunity and superinfection exclusion.

The paper maps mutation tolerability across a viral proteome, revealing structural and functional correlates and implications for drug target selection.