Author

Guangshuo Zhu

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

David A. KassiD· 2 shared Manling ZhangiD· 2 shared Adriana RamosiD· 1 shared Akira SawaiD· 1 shared An‐Chi WeiiD· 1 shared Barbara Stauch SlusheriD· 1 shared Bingxian XieiD· 1 shared Brian P O'RourkeiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

David A. KassORCID

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2 papers

Recent·Most cited

Nuclear GAPDH cascade mediates stress-dependent pathological cardiac growth

Shun Nakamura, Manling Zhang, Genri Numata, Taro Kariya, Hideyuki Sasaki, Masayuki Sasaki, Adriana Ramos, Eisuke Amiya, Masaru Hatano, Masahiko Ando, Yoichi Yasunaga, Masaki Iwakiri, Norimichi Koitabashi, Guangshuo Zhu, Tsuyoshi Tsujimura, , Eiki Takimoto

This study identifies nuclear GAPDH translocation as a mediator of stress-induced cardiac hypertrophy through BRG1-associated chromatin remodeling in mice and human patients.

bioRxiv · Nov 20, 2025 · PreprintMolecular Biology

Myocardial BDNF regulates cardiac bioenergetics through the transcription factor Yin Yang 1

Xue Yang, Manling Zhang, Bingxian Xie, Raymond Zimmerman, Qin Wang, An‐Chi Wei, Zishan Peng, Moustafa Khalifa, Michael John Reynolds, Matthew Om, Guangshuo Zhu, Djahida Bedja, Hong Jiang, Michael J. Jurczak, Sruti Shiva, , Ning Feng

This study shows that myocardial BDNF signaling via YY1 regulates cardiac bioenergetics and mitochondrial function during stress.

bioRxiv · Jan 19, 2021 · PreprintMolecular Biology