Guizhen Liu

The paper identifies VIH2 in Lotus japonicus as an inositol pyrophosphate synthase that regulates arbuscular mycorrhiza by linking phosphate starvation responses to root endosymbiosis.

The paper uses 18O-water labeling to study phosphate group dynamics in inositol phosphates across species, revealing distinct pools with different cycling behaviors.

This study uses mathematical modeling to show that 1,5-InsP8 synthesis follows a linear pathway in yeast and human cells, challenging previous assumptions about IPP metabolism.