Author

Jisun Lee

Pfizer (United States)ORCID 0000-0003-1750-0063Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aiping DongiD· 1 shared Aliakbar Khalili Yazdi· 1 shared C.H. ArrowsmithiD· 1 shared Caroline Schild‐PoulteriD· 1 shared Chakrapani SubramanyamiD· 1 shared Chan Seok LimiD· 1 shared Cong DongiD· 1 shared Dafydd R. OweniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Aiping DongORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJul 1, 2025

Highly ordered clustering of TNFα and BAFF ligand-receptor-adaptor complexes bound to lipid membranes

Chan Seok Lim, Jisun Lee, Ji Won Kim, Jie‐Oh Lee

The paper reports cryo-EM structures of TNF and BAFF ligand-receptor-adaptor complexes clustered on lipid membranes, showing that ordered clustering is essential for receptor activation.

12 citations

cryo-EMexperimental assay

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Molecular BiologyNature Chemical BiologyPeer-reviewedMay 21, 2024

A chemical probe to modulate human GID4 Pro/N-degron interactions

Dominic D. G. Owens, Matthew E. R. Maitland, Aliakbar Khalili Yazdi…·C.H. Arrowsmith

The paper introduces PFI-7, a chemical probe that inhibits GID4 Pro/N-degron interactions, revealing non-degradative roles of the CTLH complex in human cells.

41 citationstop 3%

humanproteomics

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