Thomas Eschenhagen

This study shows that BMP10 release in human atrial engineered heart tissue correlates with AF burden, with higher levels under continuous pacing, and reveals transcriptional changes linked to AF-related pathways.

This study shows that heart muscle cell contractility suppresses proliferation and that inhibiting it allows cell cycle re-entry, suggesting contractility as a key regulator of cardiac regeneration.

This study shows that mitochondrial reactive oxygen species contribute to arrhythmias in hypertrophic cardiomyopathy by disrupting calcium handling and electrical conduction.

This study shows that transplanted cardiomyocytes can electrically couple to the host myocardium and stimulate the recipient heart, triggering ventricular arrhythmias.