Author

Ethan E. Chen

Columbia UniversityORCID 0000-0003-1765-8290Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra BeckettiD· 1 shared Antonio Salcido-AlcántariD· 1 shared Carlotta RondaiD· 1 shared Christopher AcreeiD· 1 shared Crystal Lee MackalliD· 1 shared Elena SotilloiD· 1 shared Harris H. WangiD· 1 shared Jenny Y LiuiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSynthetic Biology

Alexandra BeckettORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintJun 5, 2025

A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype

Wansang Cho, Jenny Y Liu, Alexandra Beckett…·Kyle G. Daniels

This paper shows how recombining signaling motifs creates a continuous spectrum of CAR T cell phenotypes, revealing trade-offs between memory, cytotoxicity, and safety.

6 citations

humanproteomics

𝕏 PostBluesky

Molecular BiologyNature BiotechnologyPeer-reviewedNov 23, 2020

CRISPR RNA-guided integrases for high-efficiency and multiplexed bacterial genome engineering

Phuc Leo H. Vo, Carlotta Ronda, Sanne E. Klompe…·Samuel H. Sternberg

This paper introduces an improved CRISPR-based system for high-efficiency, multiplexed bacterial genome engineering using RNA-guided integrases.

346 citationstop 1%

bacteria (other)CRISPR screen

𝕏 PostBluesky