Carlotta Ronda

Half-match recombination drives bridge RNA-guided excision and off-target insertion

The paper demonstrates that half-match recombination, independent of target-site complementarity, drives bridge RNA-guided excision and off-target insertion in IS621 recombination.

Reconstructing the emergence of the human chorion via HIPPO-mediated trophoblast induction

This study uses HIPPO pathway modulation to induce human trophectoderm and reconstruct chorion development in vitro, identifying key cell types and markers.

CRISPR RNA-guided integrases for high-efficiency and multiplexed bacterial genome engineering

This paper introduces an improved CRISPR-based system for high-efficiency, multiplexed bacterial genome engineering using RNA-guided integrases.

Multiplex transcriptional characterizations across diverse and hybrid bacterial cell-free expression systems

The paper introduces DRAFTS, a method for multiplexed transcriptional measurement in cell-free systems, and shows functional differences in gene expression across bacterial species and hybrid lysates.