Christopher Acree

This study uses MIMS-EM to analyze metabolic turnover in C. elegans during dietary restriction, revealing tissue- and resource-specific changes at multiple scales.

QuantEM provides a vision transformer-based platform for EM data segmentation and analysis, achieving accurate zero-shot segmentation with less data than existing models.

This study investigates how calorie restriction modulates beta cell Ca2+ homeostasis and network connectivity, finding that CR beta cells exhibit faster, shorter Ca2+ oscillations and reduced network connectivity.

This study identifies two mobilization pathways in type V-K CASTs and shows how manipulating TnsC availability can increase their specificity to 98.1%.

The paper uses long-read sequencing to analyze transposition products of RNA-guided transposons, finding they primarily use copy-and-paste mechanisms and report engineered variants with TnsAB fusion proteins.

This paper introduces an improved CRISPR-based system for high-efficiency, multiplexed bacterial genome engineering using RNA-guided integrases.