Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery
Ramalingam Venkat Kalyana Sundaram, Atrouli Chatterjee, Manindra Bera…·Shyam Sundar Krishnakumar
The paper reconstitutes core synaptic machinery to reveal DAG's role in vesicle priming and Ca2+-triggered release, showing DAG accelerates SNAREpin assembly and affects release dynamics.